Brainstorm Cell Therapeutics Inc. is a biotechnology company focused on creating and commercializing stem cell therapies for serious neurodegenerative diseases, including ALS, PMS, and Alzheimer’s disease. Their main product, NurOwn®, is an innovative autologous cell therapy that leverages mesenchymal stem cells derived from a patient's bone marrow, which are engineered to secrete neurotrophic factors that help in neuronal protection and repair. The company has made progress in clinical trials, with the technology receiving attention for its potential to alter the course of these debilitating conditions.
The company operates through its proprietary NurOwn® platform and has engaged with the FDA in their regulatory processes, aiming to achieve approval for their therapies. Despite challenges in their Phase 3 clinical trials for ALS which did not meet their primary endpoint, the company remains committed to further studies and at the same time is exploring applications of NurOwn® in other diseases like Alzheimer’s. The business also monitors and optimizes its manufacturing capabilities to ensure compliance with good manufacturing practices, ensuring a sustainable production pathway as it progresses through clinical trials.