Viracta Therapeutics, Inc. is a clinical-stage precision oncology company that specializes in the treatment of virus-associated cancers, specifically targeting malignancies linked to the Epstein-Barr virus (EBV), a recognized carcinogen by the World Health Organization. Viracta's novel therapeutic approach, termed the 'Kick and Kill' method, involves utilizing an investigational drug called nanatinostat in combination with the antiviral agent valganciclovir. This therapy aims to activate latent EBV genes in cancer cells to enhance sensitivity to the antiviral drug, inducing programmed cell death in tumor cells. Viracta's clinical trials are actively evaluating the efficacy and safety of this combined treatment across various lymphoma types, including relapsed or refractory EBV-positive lymphomas and nasopharyngeal carcinoma.
With a focus on high unmet medical needs within the oncology sector and a unique mechanism of action that is not adequately addressed by existing therapies, Viracta is strategically positioned to make significant advancements in the treatment landscape for EBV-related cancers. The company has received Fast Track and orphan drug designations from the FDA for its treatments, which underscore its commitment to addressing serious health conditions. Continued clinical progress and potential partnership opportunities may further solidify Viracta’s role as a leader in the precision oncology market, providing hope for patients facing these challenging malignancies.